| Identification | More | [Name]
2-ETHYNYLPYRIDINE | [CAS]
1945-84-2 | [Synonyms]
2-ETHYLNYL PYRIDINE
2-ETHYNYLPYRIDINE
2-PYRIDYLACETYLENE
TIMTEC-BB SBB006619
2-ETHYNYLPYRIDINE STABILIZED 98%
2-ETHYNYLPYRIDINE, 98%, STAB. WITH 0.01% HYDROQUINONE
2-ETHYNYLPYRIDINE INHIBITED WITH 01% HYDROQUINONE
Pyridine, 2-ethynyl-(6CI, 7CI, 8CI, 9CI)
2-ETHYNYLPYRIDINE, 98+% Inhibited with 0.01% hydroquinone. Not o
2-Ethynylpyridine, 98%, Inhibited with 0.01% hydroquine
2-Ethynylpyridine ,97%
2-ETHYNYLPYRIDINE, 98+%
1-(2-Pyridinyl)ethyne
2-Pyridinylacetylene | [EINECS(EC#)]
628-748-9 | [Molecular Formula]
C7H5N | [MDL Number]
MFCD00041598 | [Molecular Weight]
103.12 | [MOL File]
1945-84-2.mol |
| Chemical Properties | Back Directory | [Appearance]
clear dark brown liquid | [Melting point ]
77-78 C | [Boiling point ]
85 °C/12 mmHg (lit.) | [density ]
1.021 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.56(lit.)
| [Fp ]
170 °F
| [storage temp. ]
2-8°C
| [form ]
Liquid | [pka]
2.31±0.12(Predicted) | [color ]
Clear dark brown | [Specific Gravity]
1.021 | [Water Solubility ]
Soluble in water. | [Detection Methods]
GC,NMR | [BRN ]
1098904 | [InChI]
InChI=1S/C7H5N/c1-2-7-5-3-4-6-8-7/h1,3-6H | [InChIKey]
NHUBNHMFXQNNMV-UHFFFAOYSA-N | [SMILES]
C1(C#C)=NC=CC=C1 | [CAS DataBase Reference]
1945-84-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
29339900 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
clear dark brown liquid | [Synthesis Reference(s)]
Synthesis, p. 364, 1981 DOI: 10.1055/s-1981-29448 | [General Description]
2-Ethynylpyridine is a pyridine derivative. | [Synthesis]
The general procedure for the synthesis of 2-ethynylpyridine from 2-pyridynyltrimethylsilane was as follows: 2-((trimethylmethylsilyl)ethynyl)pyridine (175 mg, 1.0 mmol) was dissolved in a mixed solvent of methanol/dichloromethane (2 mL/1 mL). The reaction system was cooled to 0 °C and potassium hydroxide (112 mg, 2.0 mmol) was subsequently added. After stirring the reaction mixture for 0.5 h at 0 °C, the reaction was quenched with deionized water. The reaction mixture was extracted with dichloromethane (2 x 3 mL) and the organic phases were combined. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the target product 2-ethynylpyridine (80 mg, 80% yield). | [References]
[1] Angewandte Chemie - International Edition, 2015, vol. 54, # 27, p. 7949 - 7953
[2] Angew. Chem., 2015, vol. 127, # 27, p. 8060 - 8064,5
[3] Canadian Journal of Chemistry, 2005, vol. 83, # 6-7, p. 716 - 727
[4] Dalton Transactions, 2016, vol. 45, # 25, p. 10209 - 10221
[5] Phosphorus, Sulfur and Silicon and Related Elements, 2002, vol. 177, # 5, p. 1041 - 1045 |
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