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1950635-15-0

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1950635-15-0 Structure

1950635-15-0 Structure
IdentificationBack Directory
[Name]

E3 Ligase Ligand-Linker Conjugates 20
[CAS]

1950635-15-0
[Synonyms]

Thalidomide-O-amido-C8-NH2
Cereblon Ligand-Linker Conjugates 2
E3 Ligase Ligand-Linker Conjugates 20
N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
[Molecular Formula]

C23H30N4O6
[MDL Number]

MFCD31630819
[MOL File]

1950635-15-0.mol
[Molecular Weight]

458.51
Chemical PropertiesBack Directory
[Boiling point ]

762.8±60.0 °C(Predicted)
[density ]

1.295±0.06 g/cm3(Predicted)
[pka]

10.68±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
[IC 50]

Cereblon
[References]

[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.
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