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2245697-84-9

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2245697-84-9 Structure

2245697-84-9 Structure
IdentificationBack Directory
[Name]

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
[CAS]

2245697-84-9
[Synonyms]

-ether-PEG3-amine
Thalidomide 4&rsquo
-oxyacetamide-PEG3-amine
-oxyacetamide-alkylC8-amine
Thalidomide-O-amido-PEG3-NH2 hydrochloride
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
[Molecular Formula]

C23H31ClN4O9
[MDL Number]

MFCD31656717
[MOL File]

2245697-84-9.mol
[Molecular Weight]

542.97
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

Off-white to yellow
Hazard InformationBack Directory
[Uses]

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology[1].
[IC 50]

Cereblon
[storage]

Store at -20°C
[References]

[1] Methods to induce targeted protein degradation through bifunctional molecules. WO2017007612A1.
Spectrum DetailBack Directory
[Spectrum Detail]

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride(2245697-84-9)1HNMR
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