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195867-54-0

195867-54-0 Structure

195867-54-0 Structure
IdentificationBack Directory
[Name]

6-[2-(4-IMIDAZOLYL)ETHYLAMINO]-N-(4-TRIFLUOROMETHYLPHENYL)HEPTANECARBOXAMIDE DIMALEATE
[CAS]

195867-54-0
[Synonyms]

HTMT
HTMT maleate
HTMT DIMALEATE
ODAOZWTYNWZSBY-SPIKMXEPSA-N
Histamine Trifluoromethyl Toluidide Dimaleate
6-[2-(1H-Imidazol-4-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]heptanamide
6-[[2-(1H-Imidazole-4-yl)ethyl]amino]-N-[4-(trifluoromethyl)phenyl]heptanamide
6-[2-(4-Imidazoyl)ethylamino]-N-(4-trifluoromethylphenyl)heptanecarboxamide dimaleate
6-(2-(1H-iMidazol-5-yl)ethylaMino)-N-(4-(trifluoroMethyl)phenyl)heptanaMide DIMALEATE
6-[2-(4-IMIDAZOLYL)ETHYLAMINO]-N-(4-TRIFLUOROMETHYLPHENYL)HEPTANECARBOXAMIDE DIMALEATE
[Molecular Formula]

C23H29F3N4O5
[MDL Number]

MFCD09878249
[MOL File]

195867-54-0.mol
[Molecular Weight]

498.5
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at RT
[solubility ]

DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

White solid.
[color ]

White to off-white
[Water Solubility ]

Soluble to 100 mM in water
Hazard InformationBack Directory
[Uses]

HTMT Dimaleate is an H1 and H2 receptor antagonist. These inhibitors act as antihistamine agents and are used in the treatment of allergic reactions and or stomach ulcers.
[Biological Activity]

H 1 and H 2 receptor agonist. 4x10 4 times more active than histamine in H 2 -mediated effects in natural suppressor cells. Increases intracellular Ca 2+ and IP 3 in lymphocytes through a binding site other than H 1 , H 2 or H 3 .
[IC 50]

H1 Receptor; H2 Receptor
[storage]

Desiccate at RT
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