| Identification | Back Directory | [Name]
Lu 2443 | [CAS]
19703-86-7 | [Synonyms]
Lu 2443
4,5-Dihydro-3-methyl-2-phenyl-5-thiolato-1,3,4-thiadiazol-3-ium | [Molecular Formula]
C9H8N2S2 | [MOL File]
19703-86-7.mol | [Molecular Weight]
208.303 |
| Hazard Information | Back Directory | [Description]
Lu 2443 is an antiepileptic mesoionic. | [Uses]
LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h[1]. | [References]
[1] Neidlein R, et al. Biotransformation und Pharmakokinetik von mesoionischem Didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidin-2-thion (LU 2443). Untersuchungen zur Pharmakokinetik an Ratten [Biotransformation and pharmacokinetics of mesionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-thione (LU 2443). Studies on the pharmacokinetics in rats]. Arzneimittelforschung. 1982;32(11):1447-52. PMID:6891252 |
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