| Identification | Back Directory | [Name]
4-HYDROPEROXY CYCLOPHOSPHAMIDE | [CAS]
39800-16-3 | [Synonyms]
4-HC
,2-oxide
asta6496
nsc181815
perfosfamide
4-peroxy-cpa
4-oohcyclophosphamide
4-hydroperoxyphosphamide
4-Hydroperoxycyclofosfamide
4-Hydroxyperoxycyclophophamide
4-HYDROPEROXY CYCLOPHOSPHAMIDE
perfosfaMide, 4-hydroperoxycyclophosphaMide
2-oxazophosphorine,2-(bis(2-chloroethyl)amino)-4-hydroperoxytetrahydro-2h-3
2-(bis(2-chloroethyl)amino)-4-hydroperoxytetrahydro-2h-1,3,2-oxazaphosphorin
hydroperoxide,2-(bis(2-chloroethyl)amino)tetrahydro-2h-1,3,2-oxazaphosphorin
2-[Bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
2-[Bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl Hydroperoxide
Hydroperoxide, 2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin-4-yl, p-oxide
2-[Bis(2-chloroethyl)amino]-3,4,5,6-tetrahydro-4-hydroperoxy-2H-1,3,2-oxazaphosphorin-2-oxide | [Molecular Formula]
C7H15Cl2N2O4P | [MDL Number]
MFCD01710226 | [MOL File]
39800-16-3.mol | [Molecular Weight]
293.08 |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
100-103°C | [Boiling point ]
419.9±55.0 °C(Predicted) | [density ]
1.46±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -86°C Freezer, Under Inert Atmosphere | [solubility ]
Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly), DCM | [form ]
Solid | [pka]
11.06±0.20(Predicted) | [color ]
White to Pale Yellow | [Stability:]
Hygroscopic, Temperature Sensitive | [InChI]
InChI=1S/C7H16Cl2N2O4P/c8-2-4-11(5-3-9)16(13)10-7(15-12)1-6-14-16/h7,10,12,16H,1-6H2/q-1/p-1 | [InChIKey]
ZZENMHFAKYKQCX-UHFFFAOYSA-M | [SMILES]
[O-]OC1CCOP(N(CCCl)CCCl)([O-])N1 | [CAS DataBase Reference]
39800-16-3 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A metabolite of Cyclophosphamide. Antineoplastic; bone marrow purging agent | [Definition]
ChEBI: The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. | [Biological Activity]
Active metabolite of the nitrogen mustard cyclophosphamide.
4-Hydroperoxycyclophosphamide is the active metabolite of the nitrogen mustard cyclophosphamide. 4-Hydroperoxycyclophosphamide exhibits potent antineoplastic and immunosuppressive activities. | [in vivo]
4-Hydroperoxy cyclophosphamide (200 mg/kg intraperitoneally injected) kills Caspase-independent T cells and B cells in mice[1].
| Animal Model: | BALB/c mice[1] | | Dosage: | 200 mg/kg | | Administration: | i.p. | | Result: | Exhibited a marked depletion of immature double-positive CD4 t CD8 t thymocytes and mature single-positive CD4+ and CD8+ T cells. |
| [storage]
Store at -80°C, protect from light, stored under nitrogen |
|
| Company Name: |
amyjet Gold
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4006800868;027-59626688 18371453821;18771149750 |
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http://www.amyjet.com/ |
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