| Identification | Back Directory | [Name]
[1,1'-Biphenyl]-2,2'-disulfonic acid, 4,4'-bis[[4,6-bis[[3-[[bis(2-amino-2-oxoethyl)amino]sulfonyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]-, sodium salt (1:2) | [CAS]
197366-24-8 | [Synonyms]
[1,1'-Biphenyl]-2,2'-disulfonic acid, 4,4'-bis[[4,6-bis[[3-[[bis(2-amino-2-oxoethyl)amino]sulfonyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]-, sodium salt (1:2) | [Molecular Formula]
C58H63N24NaO22S6 | [MOL File]
197366-24-8.mol | [Molecular Weight]
1663.64 |
| Hazard Information | Back Directory | [Uses]
RFI-641 is a selective inhibitor of the respiratory syncytial virus (RSV), with an IC50 of 50 nM. RFI-641 inhibit binding and fusion of enveloped virus via interaction with the viral fusion protein[1]. | [References]
[1] Nikitenko AA, et, al. The discovery of RFI-641 as a potent and selective inhibitor of the respiratory syncytial virus. Bioorg Med Chem Lett. 2001 Apr 23;11(8):1041-4. DOI:10.1016/s0960-894x(01)00150-0
[2] Razinkov V, et, al. RFI-641 inhibits entry of respiratory syncytial virus via interactions with fusion protein. Chem Biol. 2001 Jul;8(7):645-59. DOI:10.1016/s1074-5521(01)00042-4 |
|
|