| Identification | Back Directory | [Name]
N-[5-(4-methylphenyl)-1,3,4-thiadiazol-2-yl]benzamide | [CAS]
19948-85-7 | [Synonyms]
WAY-311677
N-(5-(p-Tolyl)-1,3,4-thiadiazol-2-yl)benzamide
N-[5-(4-methylphenyl)-1,3,4-thiadiazol-2-yl]benzamide
MCF-7,B16-F10,cancer,PTK2,FAK,WAY311677,Inhibitor,inhibit,WAY 311677,PTK2 protein tyrosine kinase 2,Focal adhesion kinase | [Molecular Formula]
C16H13N3OS | [MOL File]
19948-85-7.mol | [Molecular Weight]
295.359 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 10 mg/mL (33.86 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 μM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1]. | [IC 50]
FAK: 11.72 μM (IC50) | [storage]
Store at -20°C | [References]
[1] Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95. DOI:10.1016/j.bmc.2012.03.040 |
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