| Identification | Back Directory | [Name]
2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol | [CAS]
1997319-92-2 | [Synonyms]
SMARCA-BD ligand 1 for Protac
2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol
Phenol, 2-[6-amino-5-(1-piperazinyl)-3-pyridazinyl]-
SMARCA BD ligand 1 for Protac,SMARCABD ligand 1 for Protac | [Molecular Formula]
C14H17N5O | [MDL Number]
MFCD32201163 | [MOL File]
1997319-92-2.mol | [Molecular Weight]
271.32 |
| Chemical Properties | Back Directory | [Boiling point ]
569.2±50.0 °C(Predicted) | [density ]
1.290±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
8.42±0.35(Predicted) | [color ]
Light yellow to light brown |
| Hazard Information | Back Directory | [Uses]
SMARCA-BD ligand 1 for PROTAC is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1]. | [References]
[1] Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680. DOI:10.1038/s41589-019-0294-6 |
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| Company Name: |
Pharmalego
|
| Tel: |
18321033991 |
| Website: |
https://cn.pharmalego.com/ |
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