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1998119-13-3

1998119-13-3 Structure

1998119-13-3 Structure
IdentificationBack Directory
[Name]

Cy7 Alkyne
[CAS]

1998119-13-3
[Synonyms]

Cy7 Alkyne
[Molecular Formula]

C40H48ClN3O
[MDL Number]

MFCD31580105
[MOL File]

1998119-13-3.mol
[Molecular Weight]

622.29
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO, DMF, alcohols
[Appearance]

Dark green solid
[ex/em]

740/770 nm (EtOH/PBS)
[ε(extinction coefficient)]

199000 L⋅mol−1⋅cm−1
[Φ(quantum yield)]

0.3
Hazard InformationBack Directory
[Description]

Cy7 alkyne is a Cy7 linker which can be used to react in copper-catalyzed Click Chemistry reactions with azides. It has an excitation and emission wavelength at 750/773 nm.
[Chemical Properties]

Appearance: Dark green solid
ex/em: 740/770 nm (EtOH/PBS)
Extinction coefficient (ε): 199000 L??mol??1??cm??1
Quantum yield (Φ): 0.3
[Uses]

Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds[1].
[References]

[1] Zhou Y, et al. Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment. Mol Psychiatry. 2018 Apr;23(4):952-962 DOI:10.1038/mp.2017.166
[Abs/Em Maxima]

750/773 nm
[Fluoresene quantum yield]

0.3
[Extinction Coefficient]

199000
[CF260]

0.022
[CF280]

0.029
[Spectrally Similar Dyes]

Alexa Fluor® 750, RDye® 750, CF® 750 Dye, DyLight® 750
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