| Identification | Back Directory | [Name]
2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE | [CAS]
199986-75-9 | [Synonyms]
BAT5
NG 26
D6S82E
CVT-313
CS-2441
CVT-313, >98%
CVT-313(NG-26)
CDK2 INHIBITOR III
CVT 313;NG 26;CVT313;NG26
CVT-313 (CDK2 INHIBITOR III)
CVT 313;NG 26;CVT313;NG26;NG-26
Anti-ABHD16A antibody produced in rabbit
Cdk2 Inhibitor III - CAS 199986-75-9 - Calbiochem
2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE
2,2'-(9-isopropyl-6-(4-methoxybenzylamino)-9H-purin-2-ylazanediyl)diethanol
2,2'-[[6-[[(4-Methoxyphenyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]imino]bisethanol
Ethanol,2,2'-[[6-[[(4-methoxyphenyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]imino]bis- | [Molecular Formula]
C20H28N6O3 | [MDL Number]
MFCD06411412 | [MOL File]
199986-75-9.mol | [Molecular Weight]
400.47 |
| Chemical Properties | Back Directory | [Boiling point ]
652.3±65.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
≥20 mg/mL in DMSO; insoluble in H2O; ≥51.1 mg/mL in EtOH with gentle warming | [form ]
White solid | [pka]
13.95±0.10(Predicted) | [color ]
White to off-white | [biological source]
rabbit | [InChI]
1S/C20H28N6O3/c1-14(2)26-13-22-17-18(21-12-15-4-6-16(29-3)7-5-15)23-20(24-19(17)26)25(8-10-27)9-11-28/h4-7,13-14,27-28H,8-12H2,1-3H3,(H,21,23,24) | [InChIKey]
NQVIIUBWMBHLOZ-UHFFFAOYSA-N | [SMILES]
[n]1(c2nc(nc(c2nc1)NCc3ccc(cc3)OC)N(CCO)CCO)C(C)C |
| Hazard Information | Back Directory | [Uses]
CVT 313 is a potent CDK2 inhibitor. | [Biological Activity]
Cell permeable: yes''Primary Target
Cdk2/ACdk2/E''Product competes with ATP.''Reversible: yes''Target IC50: 0.5 μM for Cdk2/A and Cdk2/E; 4.2 μM for Cdk1/B; 215 μM for Cdk4/D1 | [IC 50]
cdk2/cyclin A: 0.5 μM (IC50); Cdk1/cyclin B: 4.2 μM (IC50); Cdk4/cyclin D1: 215 μM (IC50) | [storage]
Store at -20°C |
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