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2015222-31-6

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2015222-31-6 Structure

2015222-31-6 Structure
IdentificationBack Directory
[Name]

2015222-31-6
[CAS]

2015222-31-6
[Synonyms]

1-epi Regadenoson
Regadenoson Impurity 106
1H-Pyrazole-4-carboxamide, 1-(6-amino-9-α-D-ribofuranosyl-9H-purin-2-yl)-N-methyl-
[Molecular Formula]

C15H18N8O5
[MOL File]

2015222-31-6.mol
[Molecular Weight]

390.36
Chemical PropertiesBack Directory
[density ]

1.98±0.1 g/cm3(Predicted)
[pka]

13.07±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

1-epi Regadenoson is an epimer of Regadenoson (R142800). Regadenoson is a selective and potent A2A adenosine receptor agonist (1). The adenosine A2A receptor is a G-protein-coupled receptor and a key therapeutic target for oncologic, inflammatory, Parkinson''s and cardiovascular diseases (2). In rodent studies, it has been shown that co-administration of Regadenoson with Temozolomide (T017775) can increase Temozolomide concentration in the brain (3).
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