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202075-91-0

202075-91-0 Structure

202075-91-0 Structure
IdentificationBack Directory
[Name]

L-Leucinamide, L-arginyl-L-isoleucyl-L-lysyl-L-isoleucylglycyl-L-leucyl-L-phenylalanyl-L-α-aspartyl-L-glutaminyl-L-leucyl-L-seryl-L-lysyl-
[CAS]

202075-91-0
[Synonyms]

α-Pompilidotoxin
L-Leucinamide, L-arginyl-L-isoleucyl-L-lysyl-L-isoleucylglycyl-L-leucyl-L-phenylalanyl-L-α-aspartyl-L-glutaminyl-L-leucyl-L-seryl-L-lysyl-
[Molecular Formula]

C71H124N20O17
[MOL File]

202075-91-0.mol
[Molecular Weight]

1529.87
Chemical PropertiesBack Directory
[density ]

1.36±0.1 g/cm3(Predicted)
[pka]

4.19±0.10(Predicted)
[Sequence]

Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Lys-Leu-NH2
Hazard InformationBack Directory
[Uses]

α-Pompilidotoxin (α-PMTX) is a neurotoxin that can be obtained from the venom of Anoplius safnariensis. α-Pompilidotoxin reversibly and dose-dependently enhances excitatory postsynaptic currents (EPSCs). α-Pompilidotoxin is a useful tool in the field of neuroscience research[1].
[References]

[1] Konno K, et al. Alpha-pompilidotoxin (alpha-PMTX), a novel neurotoxin from the venom of a solitary wasp, facilitates transmission in the crustacean neuromuscular synapse. Neurosci Lett. 1997 Dec 5;238(3):99-102. DOI:10.1016/s0304-3940(97)00849-5
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