| Identification | Back Directory | [Name]
RO 04-6790 | [CAS]
202466-68-0 | [Synonyms]
4-amino-N-[2,6-bis(methylamino)pyrimidin-4-yl]benzenesulfonamide
4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-benzenesulfonamide
BenzenesulfonaMide, 4-aMino-N-[2,6-bis(MethylaMino)-4-pyriMidinyl]-
4-amino-n-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide dihydrobromide | [Molecular Formula]
C12H16N6O2S | [MDL Number]
MFCD02100500 | [MOL File]
202466-68-0.mol | [Molecular Weight]
308.36 |
| Chemical Properties | Back Directory | [Boiling point ]
595.8±60.0 °C(Predicted) | [density ]
1.495 | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: >10mg/mL | [form ]
solid | [pka]
9.16±0.50(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
Ro 04-6790 is a SR-6 antagonist. | [Definition]
ChEBI: 4-amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide is a sulfonamide and a member of benzenes. | [Biological Activity]
Potent and selective 5-HT 6 receptor antagonist (pK i values are 7.26 and 7.35 at rat and human 5-HT 6 receptors respectively). Displays no affinity at a range of other receptors (IC 50 > 10 μ M). Induces stretching behavior in rats in vivo . |
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BOC Sciences
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Energy Chemical
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Wuhan Topule
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SIGMA-RBI
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CHEMICAL LAND21
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