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202590-69-0

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202590-69-0 Structure

202590-69-0 Structure
IdentificationBack Directory
[Name]

CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE
[CAS]

202590-69-0
[Synonyms]

Ticalopride
202590-69-0
NORCISAPRIDE
Unii-qng273A81o
Ticalopride [inn]
CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE
4-amino-5-chloro-2-methoxy-N-((3S,4R)-3-methoxypiperidin-4-yl)benzamide
Benzamide, 4-amino-5-chloro-2-methoxy-N-[(3S,4R)-3-methoxy-4-piperidinyl]-
[Molecular Formula]

C14H20ClN3O3
[MDL Number]

MFCD07784009
[MOL File]

202590-69-0.mol
[Molecular Weight]

313.78
Hazard InformationBack Directory
[Uses]

(+)-Norcisapride (Ticalopride) is a potent 5-HT4 agonist and a 5-HT3 antagonist. (+)-Norcisapride has activity in animals models of constipation[1].
[IC 50]

5-HT4 Receptor; 5-HT3 Receptor
[References]

[1] Liming Shao, et al. mu-Opioid/5-HT4 dual pharmacologically active agents-efforts towards an effective opioid analgesic with less GI and respiratory side effects (Part I). Bioorg Med Chem Lett. 2009 Oct 1;19(19):5679-83. DOI:10.1016/j.bmcl.2009.08.016
Spectrum DetailBack Directory
[Spectrum Detail]

CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE(202590-69-0)1HNMR
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