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20263-06-3

20263-06-3 Structure

20263-06-3 Structure
IdentificationMore
[Name]

DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID
[CAS]

20263-06-3
[Synonyms]

AP-3
DL-AP3
3-Phosphonoalanine.
3-Phosphono-DL-alanine
3-Phosphono-DL-alanine, AP-3
2-aMino-3-phosphonopropanoic acid
DL-2-AMINO-3-PHOSPHONOPROPANOIC ACID
DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID
DL-2-Amino-3-phosphonopropionic acidDL-AP3
DL-2-Amino-3-phosphonopropionic acid (AP3)
rac-(2R*)-2-Amino-3-phosphonopropionic acid
D,L-2-Amino-3-phosphonopropionic acid, 98 %
DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID USP/EP/BP
[Molecular Formula]

C3H8NO5P
[MDL Number]

MFCD00014350
[Molecular Weight]

169.07
[MOL File]

20263-06-3.mol
Chemical PropertiesBack Directory
[Appearance]

white to almost white powder
[Melting point ]

227-229 °C(lit.)
[storage temp. ]

0-6°C
[solubility ]

Water (Slightly, Heated)
[form ]

solid
[color ]

Light Brown
[CAS DataBase Reference]

20263-06-3(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[HS Code ]

29310099
Hazard InformationBack Directory
[Chemical Properties]

white to almost white powder
[Uses]

DL-2-Amino-3-phosphonopropionic acid (AP3) is an inhibitor of phosphoserine phosphatase and mGluR. Also known as the antagonist of a receptor that is coupled to phosphoinositide metabolism in brain slices. D,L-2-Amino-3-phosphonopropionic acid is also an inhibitor of metabotropic glutamate receptors in rat brain.
[Definition]

ChEBI: 2-amino-3-phosphonopropanoic acid is a non-proteinogenc alpha-amino acid that is alanine in which one of the hydrogens of the terminal methyl group has been replaced by a dihydroxy(oxido)-lambda(5)-phosphanyl group. It has a role as a metabotropic glutamate receptor antagonist and a human metabolite. It is a non-proteinogenic alpha-amino acid, a member of phosphonic acids and an alanine derivative.
[Biological Activity]

Competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
[storage]

Store at RT
Spectrum DetailBack Directory
[Spectrum Detail]

DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID(20263-06-3)1HNMR
DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID(20263-06-3)IR
DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID(20263-06-3)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

DL-2-Amino-3-phosphonopropionic acid(20263-06-3)
[Sigma Aldrich]

20263-06-3(sigmaaldrich)
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