| Identification | Back Directory | [Name]
Diorcinal | [CAS]
20282-75-1 | [Synonyms]
Diorcinal
diorcinol
Phenol, 3,3'-oxybis[5-methyl-
3-(3-Hydroxy-5-methylphenoxy)-5-methylphenol | [Molecular Formula]
C14H14O3 | [MOL File]
20282-75-1.mol | [Molecular Weight]
230.26 |
| Hazard Information | Back Directory | [Uses]
Diorcinol is a potent SHP1 inhibitor with an IC50 value of 0.96 μM. Diorcinol can be isolated from Aspergillus sydowii. Diorcinol has good blood-brain barrier penetration and can be used for diabetes research[1]. | [Definition]
ChEBI: Diorcinol is an aromatic ether that is diphenyl ether in which both phenyl groups are substituted at position 3 by a hydroxy group and at position 5 by a methyl group. It has a role as a metabolite, a fungal metabolite and a marine metabolite. It is an aromatic ether and a member of phenols. | [References]
[1] Shi X, et al. Chemical Epigenetic Regulation Secondary Metabolites Derived from Aspergillus sydowii DL1045 with Inhibitory Activities for Protein Tyrosine Phosphatases. Molecules. 2024 Jan 31;29(3):670. DOI:10.3390/molecules29030670 |
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