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2032436-79-4

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2032436-79-4 Structure

2032436-79-4 Structure
IdentificationBack Directory
[Name]

Isoquinoline, 2-(4-fluorophenyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-
[CAS]

2032436-79-4
[Synonyms]

MAO-B-IN-15
Isoquinoline, 2-(4-fluorophenyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-
[Molecular Formula]

C17H18FNO2
[MOL File]

2032436-79-4.mol
[Molecular Weight]

287.33
Chemical PropertiesBack Directory
[Boiling point ]

433.7±45.0 °C(Predicted)
[density ]

1.178±0.06 g/cm3(Predicted)
[pka]

4.78±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

MAO-B-IN-15 is a selective MAO-B inhibitor (IC50: 13.5 μM) that forms π-π interaction with Tyr 326 residue. MAO-B-IN-15 can be used in the research of Parkinson’s disease[1].
[IC 50]

hMAO-B: 13.5 μM (IC50); hMAO-A: >100 μM (IC50)
[References]

[1] Makito Yamada, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. https://doi.org/10.1021/acsmedchemlett.2c00228.
2032436-79-4 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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