| Identification | Back Directory | [Name]
Z-Leu-Leu-Tyr-a-keto aldehyde | [CAS]
204649-66-1 | [Synonyms]
Z-Leu-Leu-Tyr-a-keto aldehyde
Z-Leu-Leu-Tyr-α-keto aldehyde
L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-[(4-hydroxyphenyl)methyl]-2,3-dioxopropyl]- | [Molecular Formula]
C30H39N3O7 | [MDL Number]
MFCD03788098 | [MOL File]
204649-66-1.mol | [Molecular Weight]
553.65 |
| Chemical Properties | Back Directory | [Boiling point ]
813.3±65.0 °C(Predicted) | [density ]
1.188±0.06 g/cm3(Predicted) | [pka]
9.82±0.15(Predicted) | [Sequence]
{Cbz}-Leu-Leu-Tyr-{COCHO} |
| Hazard Information | Back Directory | [Uses]
Z-Leu-Leu-Tyr-COCHO is a potent chymotrypsin-like activity inhibitor with a Ki value of 3.0 nM[1]. | [References]
[1] Lynas JF, et, al. Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl alpha-keto aldehydes (glyoxals). Bioorg Med Chem Lett. 1998 Feb 17;8(4):373-8. DOI:10.1016/s0960-894x(98)00030-4 |
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