75873-85-7

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75873-85-7 Structure

Identification	Back Directory
[Name] N-CBZ-LEU-LEU-GLU BETA-NAPHTHYLAMIDE
[CAS] 75873-85-7
[Synonyms] Z-LLG-βNA Z-LLG-βNA cbz-lleβ-na Z-Leu-Leu-Glu-βNA Z-Leu-Leu-Glu-bNA Z-Leu-Leu-Glu-βNA CBZ-Leu-Leu-Glu-Βna Z-LEU-LEU-GLU-BETANA Cbz-LLE β-naphthylamine z-leu-leu-glu β-naphthylamide N-CBZ-LEU-LEU-GLU β-NAPHTHYLAMIDE N-cbz-leu-leu-glu B-naphthylamide CBZ-LEU-LEU-GLU-BETA-NAPHTHYLAMIDE N-CBZ-LEU-LEU-GLU BETA-NAPHTHYLAMIDE Z-Leu-Leu-Glu beta-naphthylamide >=98%, powder N-carbobenzyloxy-Leu-Leu-Glu beta-naphthylamide carbobenzoxyleucyl-leucyl-glutamyl-2-naphthylamide N-[(Phenylmethoxy)carbonyl]-L-leucyl-L-leucyl-N-2-naphthalenyl-L-α-glutamine L-α-Glutamine, N-[(phenylmethoxy)carbonyl]-L-leucyl-L-leucyl-N-2-naphthalenyl-
[Molecular Formula] C35H44N4O7
[MDL Number] MFCD00058505
[MOL File] 75873-85-7.mol
[Molecular Weight] 632.75

Chemical Properties	Back Directory
[storage temp. ] −20°C
[solubility ] THF: 25mg/mL, clear, colorless
[form ] powder
[color ] white
[Sequence] Z-Leu-Leu-Glu-βNA
[InChIKey] MIYHULQEZFNUGE-UHFFFAOYSA-N
[SMILES] CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)Nc2ccc3ccccc3c2

Safety Data	Back Directory
[Symbol(GHS) ] GHS08
[Signal word ] Warning
[Hazard statements ] H351
[Precautionary statements ] P281
[Hazard Codes ] Xn
[Risk Statements ] 40
[Safety Statements ] 22-36
[WGK Germany ] 3
[Storage Class] 11 - Combustible Solids
[Hazard Classifications] Carc. 2

Hazard Information	Back Directory
[Uses] Z-Leu-Leu-Glu-βNA (Z-Leu-Leu-Glu-β-naphthylamide) is a substrate for determination of the glutamylpeptidyl-peptide hydrolase activity of the 20S proteasome[1].
[References] [1] Reidlinger J, et al. Catalytic properties of 26 S and 20 S proteasomes and radiolabeling of MB1, LMP7, and C7 subunits associated with trypsin-like and chymotrypsin-like activities. J Biol Chem. 1997 Oct 3;272(40):24899-905. DOI:10.1074/jbc.272.40.24899

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