| Identification | Back Directory | [Name]
N-Boc-N-bis(PEG2-acid) | [CAS]
2054339-01-2 | [Synonyms]
Acid-apeg4-acid n-boc
N-Boc-N-bis(PEG2-acid)
4,7,13,16-Tetraoxa-10-azanonadecanedioic acid, 10-[(1,1-dimethylethoxy)carbonyl]- | [Molecular Formula]
C19H35NO10 | [MDL Number]
MFCD29912844 | [MOL File]
2054339-01-2.mol | [Molecular Weight]
437.482 |
| Chemical Properties | Back Directory | [Boiling point ]
590.6±50.0 °C(Predicted) | [density ]
1.189±0.06 g/cm3(Predicted) | [storage temp. ]
Storage temp. 2-8°C | [form ]
Viscous Liquid | [pka]
3.98±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
N-Boc-N-bis(PEG2-acid) is a branched PEGylation reagent, it can react with primary amino groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Uses]
N-Boc-N-bis(PEG2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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