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1919044-99-7

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1919044-99-7 Structure

1919044-99-7 Structure
IdentificationBack Directory
[Name]

NH-(PEG2-acid)2
[CAS]

1919044-99-7
[Synonyms]

Acid-apeg4-acid
NH-(PEG2-acid)2
NH-bis(PEG2-C2-acid)
NH-bis(PEG2-acid) HCl salt
4,7,13,16-Tetraoxa-10-azanonadecanedioic acid
[Molecular Formula]

C14H27NO8
[MDL Number]

MFCD29912839
[MOL File]

1919044-99-7.mol
[Molecular Weight]

337.37
Chemical PropertiesBack Directory
[Boiling point ]

521.6±50.0 °C(Predicted)
[density ]

1.191±0.06 g/cm3(Predicted)
[pka]

3.97±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Description]

NH-bis(PEG2-acid) HCl salt is an anqueous soluble branched compound with a central amino group and two terminal carboxylic acids. The amino group is reactive with activated NHs ester, Carboxylic group can react with primary amino groups.
[Uses]

NH-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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