| Identification | Back Directory | [Name]
NH-(PEG3-Boc)2 | [CAS]
2055024-51-4 | [Synonyms]
NH-(PEG3-Boc)2
NH-bis(PEG3-Boc)
NH-bis(PEG3-C2-NH-Boc)
5,8,11,17,20,23-Hexaoxa-2,14,26-triazaheptacosanedioic acid, 1,27-bis(1,1-dimethylethyl) ester
tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethylamino]ethoxy]ethoxy]ethoxy]ethyl]carbamate | [Molecular Formula]
C26H53N3O10 | [MDL Number]
MFCD29918213 | [MOL File]
2055024-51-4.mol | [Molecular Weight]
567.71 |
| Chemical Properties | Back Directory | [Boiling point ]
636.7±55.0 °C(Predicted) | [density ]
1.072±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [pka]
11.92±0.46(Predicted) |
| Hazard Information | Back Directory | [Description]
NH-bis(PEG3-Boc) is a PEG molecule containing an amino (NH2) group with two Boc protected amines. Amino group is reactive with carboxylic acids, activated NHS esters, carbonyls. The protected amine can be deprotected under acidic conditions. | [Uses]
NH-bis(PEG3-C2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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