Identification | Back Directory | [Name]
NH-bis(PEG4-OH) | [CAS]
63721-06-2 | [Synonyms]
NH-bis-PEG5 NH-bis(PEG4-OH) 3,6,9,12,18,21,24,27-Octaoxa-15-azanonacosane-1,29-diol | [Molecular Formula]
C20H43NO10 | [MDL Number]
MFCD30536158 | [MOL File]
63721-06-2.mol | [Molecular Weight]
457.56 |
Hazard Information | Back Directory | [Description]
NH-bis(PEG4-OH) is a branched PEG4 reagentr. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls, etc. The hydroxy groups enable further derivatization or replacement with other reactive functional groups. | [Uses]
NH-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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