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63721-06-2

63721-06-2 Structure

63721-06-2 Structure
IdentificationBack Directory
[Name]

NH-bis(PEG4-OH)
[CAS]

63721-06-2
[Synonyms]

NH-bis-PEG5
NH-bis(PEG4-OH)
3,6,9,12,18,21,24,27-Octaoxa-15-azanonacosane-1,29-diol
[Molecular Formula]

C20H43NO10
[MDL Number]

MFCD30536158
[MOL File]

63721-06-2.mol
[Molecular Weight]

457.56
Hazard InformationBack Directory
[Description]

NH-bis(PEG4-OH) is a branched PEG4 reagentr. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls, etc. The hydroxy groups enable further derivatization or replacement with other reactive functional groups.
[Uses]

NH-bis-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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