| Identification | Back Directory | [Name]
5-FLUOROOROTIC ACID HYDRATE, 98 | [CAS]
207291-81-4 | [Synonyms]
5-Fluor-uracil-4-carbonsure
5-FLUOROOROTIC ACID HYDRATE, 98
2,6-Dihydroxy-5-fluor-pyrimidin-4-carbonsure
2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid, 5-Fluorouracil-4-carboxylic acid | [EINECS(EC#)]
211-876-0 | [Molecular Formula]
C5 H3 F N2 O4 . x H2 O | [MDL Number]
MFCD00150658 | [MOL File]
207291-81-4.mol | [Molecular Weight]
174.09 |
| Chemical Properties | Back Directory | [Appearance]
white to light orange crystalline powder | [Melting point ]
278 °C (dec.)(lit.) | [storage temp. ]
−20°C | [solubility ]
4 M NH4OH: soluble50mg/mL, clear, faintly yellow | [form ]
Solid | [color ]
White to Pale Yellow | [biological source]
synthetic | [CAS DataBase Reference]
207291-81-4 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light orange crystalline powder | [Uses]
5-Fluoroorotic acid hydrate has also been used as a counter-selection agent to screen L. lactis (multi) peptidase knockout mutants and C. albicans. It has been used in synthesis of 5-fluoroorotidine 5′-monophosphate (FOMP). | [Biochem/physiol Actions]
5-Fluoroorotic acid is a selective inhibitor of rRNA synthesis in mammals. |
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