Identification | Back Directory | [Name]
1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride | [CAS]
207572-69-8 | [Synonyms]
1-PIPERIDINYLETHYL-1H-INDOLE-3-CARBOXYLATE HYDROCHLORIDE SB-203186,SB 203186,SB203186,SB 203186 hydrochloride,carbachol,SB203186 hydrochloride,peristaltic,5-HT Receptor,Inhibitor,Serotonin Receptor,inhibit,5-hydroxytryptamine Receptor,tachycardia,reflex | [Molecular Formula]
C16H21ClN2O2 | [MDL Number]
MFCD04037547 | [MOL File]
207572-69-8.mol | [Molecular Weight]
308.81 |
Chemical Properties | Back Directory | [storage temp. ]
4°C, protect from light | [solubility ]
Water:10.0(Max Conc. mg/mL);32.46(Max Conc. mM) | [form ]
Powder | [color ]
White to off-white | [Water Solubility ]
Soluble to 100 mM in water |
Hazard Information | Back Directory | [Uses]
SB203186 is a potent 5HT4?serotonin receptor antagonist. | [in vivo]
Intraduodenally administered SB-203186 (0.3-3 mg/kg) to new-born Camborough piglets produced blockade of 5-HT-evoked tachycardia which was maximal after 20 min and lasted for more than 3 h with 0.3 mg/kg[1].
SB-203186 (0.1-3mg/kg, i.v.) surmountably antagonised 5-HT-evoked tachycardia in anaesthetized Yucatan minipigs or new-born Camborough piglets with similar potency[1].
| [storage]
4°C, protect from light |
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BOC Sciences
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https://www.bocsci.com |
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