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208193-48-0

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208193-48-0 Structure

208193-48-0 Structure
IdentificationBack Directory
[Name]

5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite
[CAS]

208193-48-0
[Synonyms]

2’-Deoxy-2’-fluoro-5-Me-ara-U-3’-CED-phosphoramidite
1-[2-DEOXY-2-FLUORO-5-O-DMTr-B-D-ARABINOFURANOSYL]- THYMINE-3-O-CE-AMIDITE
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite
5’-O-(4,4’-Dimethoxytrityl)-2’-deoxy-2’-fluoro-5-methyl-b-D-arabinouridine-3’-CED-phosphoramidite
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite
2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-methyl-
[Molecular Formula]

C40H48FN4O8P
[MDL Number]

MFCD15145401
[MOL File]

208193-48-0.mol
[Molecular Weight]

762.82
Chemical PropertiesBack Directory
[solubility ]

DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml
[pka]

9.55±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
[References]

[1] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980
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