2091887-74-8

Directory

2091887-74-8 Structure

Identification	Back Directory
[Name] ALP/Carbonic anhydrase-IN-1
[CAS] 2091887-74-8
[Synonyms] ALP/Carbonic anhydrase-IN-1
[Molecular Formula] C15H16N2
[MOL File] 2091887-74-8.mol
[Molecular Weight] 224.3

Chemical Properties	Back Directory
[Boiling point ] 337.944±24.00 °C(Press: 760.00 Torr)(predicted)
[density ] 1.104±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] 7.175±0.40(predicted)
[color ] Off-white to light yellow

Hazard Information	Back Directory
[Uses] ALP/Carbonic anhydrase-IN-1 (Compound 1e) is a dual carbonic anhydrase (CA) and alkaline phosphatase (ALP) inhibitor. ALP/Carbonic anhydrase-IN-1 shows IC50 values of 0.44 μM, 1.61 μM, 0.51 μM, and 0.107 μM for CA-II, CA-IX, CA-XII, and ALP, respectively[1].
[IC 50] CA Ⅱ: 0.44 μM (IC₅₀); CA Ⅸ: 1.61 μM (IC₅₀); CA XII: 0.51 μM (IC₅₀); Alkaline phosphatase: 0.107 μM (IC₅₀)
[References] [1] Salman Alrokayan, et al. [1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase. BMC Chem. 2023 Oct 25;17(1):142. DOI:10.1186/s13065-023-01052-8

2091887-74-8 suppliers list

Tags:2091887-74-8 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login