| Identification | Back Directory | [Name]
Eplerenone Impurity 19 | [CAS]
209253-73-6 | [Synonyms]
4,5α-Epoxy Eplerenone
Eplerenone Impurity 19
(1aS,2R,4aS,4bR,5aR,6aS,10R,11aS)-methyl 4a,6a-dimethyl-2,5-dioxohexadecahydro-3H-spiro[cyclopent
Pregnane-7,21-dicarboxylic acid, 4,5:9,11-diepoxy-17-hydroxy-3-oxo-, γ-lactone, methyl ester, (4α,5α,7α,11α,17α)- (9CI) | [Molecular Formula]
C24H30O7 | [MOL File]
209253-73-6.mol | [Molecular Weight]
430.5 |
| Chemical Properties | Back Directory | [Melting point ]
>249°C (dec.) | [Boiling point ]
610.1±55.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
4,5α-Epoxy Eplerenone is an impurity of Eplerenone (E588775), a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. |
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