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2097010-30-3

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2097010-30-3 Structure

2097010-30-3 Structure
IdentificationBack Directory
[Name]

HOOCCH2CH2O-PEG10-CH2CH2COOH
[CAS]

2097010-30-3
[Synonyms]

HOOCCH2CH2-PEG10-CH2CH2COOH
HOOCCH2CH2O-PEG10-CH2CH2COOH
4,7,10,13,16,19,22,25,28,31,34-Undecaoxaheptatriacontanedioic acid
[Molecular Formula]

C26H50O15
[MDL Number]

MFCD28385481
[MOL File]

2097010-30-3.mol
[Molecular Weight]

602.67
Chemical PropertiesBack Directory
[Boiling point ]

684.6±55.0 °C(Predicted)
[density ]

1.165±0.06 g/cm3(Predicted)
[pka]

3.97±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Bis-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Biological Activity]

Bis-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[IC 50]

PEGs
[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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