| Identification | Back Directory | [Name]
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide | [CAS]
2098545-98-1 | [Synonyms]
N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-5-ethyl-6-[ethyl(tetrahydropyran-4-yl)amino]-2-(1-piperidylmethyl)benzofuran-4-carboxamide
4-Benzofurancarboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-ethyl-6-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-2-(1-piperidinylmethyl)- | [Molecular Formula]
C32H44N4O4 | [MDL Number]
MFCD32670487 | [MOL File]
2098545-98-1.mol | [Molecular Weight]
548.72 |
| Chemical Properties | Back Directory | [Boiling point ]
735.3±60.0 °C(Predicted) | [density ]
1.168±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
14.01±0.46(Predicted) | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Uses]
EZH2-IN-15 is a EZH2 inhibitor. EZH2-IN-15 has anti-tumor activity, and can be used for research of H3K27me3-dependent tumors[1]. | [References]
[1] Dale B, et al. Targeting Triple-Negative Breast Cancer by a Novel Proteolysis Targeting Chimera Degrader of Enhancer of Zeste Homolog 2. ACS Pharmacol Transl Sci. 2022 Jun 24;5(7):491-507. DOI:10.1021/acsptsci.2c00100 |
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