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2098836-63-4

2098836-63-4 Structure

2098836-63-4 Structure
IdentificationBack Directory
[Name]

E3 ligase Ligand-Linker Conjugates 29
[CAS]

2098836-63-4
[Synonyms]

VH032-thiol-C6-NH2
VHL Ligand-Linker Conjugates 14
E3 ligase Ligand-Linker Conjugates 29
[Molecular Formula]

C29H43N5O4S2
[MDL Number]

MFCD32062702
[MOL File]

2098836-63-4.mol
[Molecular Weight]

589.81
Chemical PropertiesBack Directory
[Boiling point ]

868.6±65.0 °C(Predicted)
[density ]

1.232±0.06 g/cm3(Predicted)
[pka]

14.05±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.
[IC 50]

VHL
[References]

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329
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