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21009-05-2

21009-05-2 Structure

21009-05-2 Structure
IdentificationBack Directory
[Name]

(15E)-12β-Hydroxy-18-norsenecionan-11,16-dione
[CAS]

21009-05-2
[Synonyms]

Nilgirine
(15E)-12β-Hydroxy-18-norsenecionan-11,16-dione
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5-methyl-, (3E,5R,6S,14aR,14bR)- (9CI)
[Molecular Formula]

C17H23NO5
[MOL File]

21009-05-2.mol
[Molecular Weight]

321.37
Chemical PropertiesBack Directory
[Melting point ]

127-8°C
[Boiling point ]

571.272±50.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.279±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka]

12.738±0.40(predicted)
Hazard InformationBack Directory
[Description]

A hepatotoxic alkaloid, this base has so far been obtained only from the seeds of Crotalaria mucronata Desv. indigenous to Nilgiris in Southern India. The same species grown in other regions is found to contain Usaramine (q.v.). The alkaloid has [α]20D + 31.5° (EtOH) and the structure has been elucidated on the basis of the alkaline hydrolysis products and the NMR and mass spectra.
[Uses]

Nilgirine is a Alkaloids product that can be isolated from the herbs of Crotalaria mucronata[1].
[References]

Atal et aI., Tetrahedron Lett., 5606 (1968)
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