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210181-19-4

210181-19-4 Structure

210181-19-4 Structure
IdentificationBack Directory
[Name]

JE 2178
[CAS]

210181-19-4
[Synonyms]

JE2178
JE-2178
JE 2178
[Molecular Formula]

C35H51N5O6S
[MOL File]

210181-19-4.mol
[Molecular Weight]

669.88
Hazard InformationBack Directory
[Uses]

JE-2178 is an orally available HIV-1 protease inhibitor with IC50 and Ki values are 15 and 0.318 nM respectively. JE-2178 has antiviral activity[1].
[References]

[1] Mimoto T, et al. Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere. Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1310-26. DOI:10.1248/cpb.48.1310
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