| Identification | Back Directory | [Name]
N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine | [CAS]
210344-99-3 | [Synonyms]
Ac-Trp-Glu-His-Asp-AFC trifluoroacetate salt
N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine
N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine
L-α-Asparagine, N-acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- | [Molecular Formula]
C38H37F3N8O11 | [MDL Number]
MFCD01862607 | [MOL File]
210344-99-3.mol | [Molecular Weight]
838.75 |
| Chemical Properties | Back Directory | [Boiling point ]
1351.5±65.0 °C(Predicted) | [density ]
1.528±0.06 g/cm3(Predicted) | [pka]
4.07±0.10(Predicted) | [Appearance]
White to yellow Solid |
| Hazard Information | Back Directory | [Description]
Ac-WEHD-AFC is a fluorogenic substrate for group I caspases including caspase-1, -4, and -5. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. | [Uses]
N-Acetyl-L-tryptophyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine is a fluorogenic substrate that can be cleaved by group I caspases. | [IC 50]
Caspase-1 | [Excitation / Emission Maximum]
400 nm/505 nm | [Sequene]
Ac-Trp-Glu-His-Asp-Unk |
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| Company Name: |
Ontores Biotech
|
| Telephone: |
0571-88760729 18072970094 |
| Website: |
www.ontoresinc.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|