ChemicalBook--->CAS DataBase List--->21055-37-8

21055-37-8

21055-37-8 Structure

21055-37-8 Structure
IdentificationMore
[Name]

METHYL 2-ISOTHIOCYANATOACETATE
[CAS]

21055-37-8
[Synonyms]

METHYL 2-ISOTHIOCYANATOACETATE
METHYL ISOTHIOCYANATOACETATE
thyl 2-isothiocyanatoacetate
METHYL 2-ISOTHIOCYANOACETATE
Isothiocyanatoacetic acid methyl ester
[EINECS(EC#)]

670-339-2
[Molecular Formula]

C4H5NO2S
[MDL Number]

MFCD00041119
[Molecular Weight]

131.15
[MOL File]

21055-37-8.mol
Chemical PropertiesBack Directory
[Boiling point ]

138 °C
[density ]

1.210
[refractive index ]

1.5200
[Fp ]

137-138°C/35mm
[Sensitive ]

Moisture Sensitive
[BRN ]

2074764
[CAS DataBase Reference]

21055-37-8(CAS DataBase Reference)
Questions And AnswerBack Directory
[Uses]

2-Isothiocyanoacetate methyl ester can be used as a pharmaceutical synthesis intermediate. It can be prepared by reacting glycine methyl ester hydrochloride with phosgene. It can be used to prepare compound (R)-2-(3(1-(4-fluorophenyl)ethyl)thiourea)acetate methyl ester. This compound can be used as a secretase regulator (including inhibitors, antagonists, etc.) to treat various diseases, including central nervous system disorders such as neurodegenerative diseases such as Alzheimer's disease, and other diseases related to amyloid protein deposition.
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R34:Causes burns.
R42:May cause sensitization by inhalation.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
[RIDADR ]

2927
[HazardClass ]

6.1
[PackingGroup ]

II
[HS Code ]

2930909899
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Methyl 2-isothiocyanatoacetate, 98%(21055-37-8)
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