Log in | Join Free | china | japan | germany
ChemicalBook--->CAS DataBase List--->211096-49-0

211096-49-0

Request For Quotation
211096-49-0 Structure

211096-49-0 Structure
IdentificationBack Directory
[Name]

GSK-CXCR2
[CAS]

211096-49-0
[Synonyms]

GSK-CXCR2
SB 265610
SB265610 >=98% (HPLC)
N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea
Urea, N-(2-bromophenyl)-N'-(4-cyano-1H-benzotriazol-7-yl)-
1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d] [1,2,3]triazol-7-yl)urea
[Molecular Formula]

C14H9BrN6O
[MDL Number]

MFCD09971124
[MOL File]

211096-49-0.mol
[Molecular Weight]

357.16
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble15mg/mL, clear
[form ]

powder
[color ]

white to light brown
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P280-P305+P351+P338
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

SB 265610 is an anti-tumor pharmaceutical developed to act as an antagonist to cysteine-amino acid-cysteine (CXC) chemokines receptor 2 antagonist.
[Biological Activity]

Potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca 2+ mobilization (IC 50 values are 3.4 and 6800 nM respectively). Inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo .
[Biochem/physiol Actions]

SB265610 is a potent and selective CXCR2 chemokine receptor antagonist. It has a Kd = 2.5 nM.
[storage]

Store at RT
Spectrum DetailBack Directory
[Spectrum Detail]

GSK-CXCR2(211096-49-0)1HNMR
211096-49-0 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: Aromsyn Co., Ltd.
Tel: +86-0571-85585865 +8613336024896 , +8613336024896
Website: https://www.aromsyn.com/
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581 , +undefined18051384581
Website: https://www.chemhifuture.com/
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Website: https://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm
Company Name: AdooQ Bioscience CHINA  
Tel: 025-58849295 18951903616;
Website: http://www.adooq.cn
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
Website: http://www.bioll.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shanghai Changyan Chem & Tech Co., Ltd.  
Tel: 021-021-20242659 18930833303
Website: http://www.changyanchem.com
Company Name: ShangHai Biochempartner Co.,Ltd  
Tel: 17754423994 17754423994
Website: https://www.biochempartner.com
Company Name: Shanghai Rechem science Co., Ltd.  
Tel: 21-31433387 15618786686
Website: cn.rechemscience.com
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
Tel: 010-50973130 4009686088
Website: http://www.solarbio.com
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Website: www.bio-fount.com
Company Name: DC Chemicals  
Tel: 021-58447131 13564518121
Website: https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm
Company Name: Changzhou Chenhong Biotechnology Co., Ltd.  
Tel: 0519-85788828 13775037613
Website: http://www.chemrenblock.com/
Tags:211096-49-0 Related Product Information
607742-69-8 1884220-36-3 942123-43-5 2073059-56-8 380899-24-1 937270-47-8 152121-47-6 152239-46-8 1204918-72-8