| Identification | Back Directory | [Name]
HS024 | [CAS]
212370-59-7 | [Synonyms]
HS024
M.W. 1266.50 C58H79N19O10S2
AC-CYS-NLE-ARG-HIS-D-2-NAL-ARG-TRP-GLY-CYS-NH2
AC-CYS-NLE-ARG-HIS-D-NAL(2)-ARG-TRP-GLY-CYS-NH2
Acetyl-(Cys3,Nle,Arg,D-2-Nal,Cys11)-α-MSH (3-11) amide
Acetyl-(Cys3,Nle4,Arg5,D-2-Nal7,Cys11)-a-MSH (3-11) aMide
Acetyl-(Cys3,Nle4,Arg5,D-2-Nal7,Cys11)-α-MSH (3-11) amide
Acetyl-(Cys3,Nle4,Arg5,D-2-Nal7,Cys11)-Alpha-MSH (3-11) amide
Acetyl-(Cys3,Nle4,Arg5,D-2-Nal7,Cys11)-α-MSH (3-11) aMide
HS024
(AC-CYS3,NLE4,ARG5,D-ALA(2-NAPHTHYL)7,CYS11)-ALPHA-MSH (3-11) AMIDE
AC-CYS-NLE-ARG-HIS-D-2-NAL-ARG-TRP-GLY-CYS-NH2 TRIFLUOROACETATE SALT
Ac-Cys-Nle-Arg-His-D-Nal(2)-Arg-Trp-Gly-Cys-NH2 (Disulfide bridge Cys1-Cys9)
(ACETYL-CYS3,NLE4,ARG5,D-2-NAL7,CYS11)-ALPHA-MSH (3-11) AMIDE TRIFLUOROACETATE SALT
[Acetyl-Cys3, Nle4, Arg5, D-2-Nal7, Cys11]-α-Melanocyte Stimulating Hormone Fragment 3-11 amide
L-Cysteinamide, N-acetyl-L-cysteinyl-L-norleucyl-L-arginyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophylglycyl-, cyclic (1→9)-disulfide | [Molecular Formula]
C58H79N19O10S2 | [MDL Number]
MFCD02179659 | [MOL File]
212370-59-7.mol | [Molecular Weight]
1266.5 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [form ]
Powder | [pka]
12.79±0.70(Predicted) | [Water Solubility ]
Soluble to 0.50 mg/ml in water |
| Hazard Information | Back Directory | [Uses]
HS024 is a selective MC4 receptor antagonist, with Kis of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake[1]. | [storage]
Desiccate at -20°C | [References]
[1] Kask A, et al. Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo. Endocrinology. 1998;139(12):5006-5014. DOI:10.1210/endo.139.12.6352 |
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