| Identification | Back Directory | [Name]
D-Phenylalaninamide, N-acetyl-D-histidyl-D-phenylalanyl-D-isoleucyl-D-arginyl-D-tryptophyl- | [CAS]
212966-15-9 | [Synonyms]
AC178335
AC-178335
AC 178335
D-Phenylalaninamide, N-acetyl-D-histidyl-D-phenylalanyl-D-isoleucyl-D-arginyl-D-tryptophyl- | [Molecular Formula]
C49H63N13O7 | [MDL Number]
MFCD19105497 | [MOL File]
212966-15-9.mol | [Molecular Weight]
946.11 |
| Hazard Information | Back Directory | [Uses]
AC-178335 is a SRIF antagonist, with a Ki of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50=5.1 μM). AC-178335 induces GH release in anesthetized rats[1]. | [References]
[1] Baumbach WR, et, al. A linear hexapeptide somatostatin antagonist blocks somatostatin activity in vitro and influences growth hormone release in rats. Mol Pharmacol. 1998 Nov;54(5):864-73. DOI:10.1124/mol.54.5.864 |
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