| Identification | Back Directory | [Name]
(+)-MAGNOFLORINE IODIDE | [CAS]
2141-09-5 | [Synonyms]
escholin
Esholine
escholine
THALICTRIN
Aids002649
Magflorine
Aids-002649
THALICTRINE
MAGNOFLORINE
(+)-Magnoflorine
Aporphine alkaloid
alpha-Magnoflorine
Corytuberine Methosalt
(+)-MAGNOFLORINE IODIDE
MAGNOFLORINE IODIDE, (+)-
1,11-dihydroxy-2,10-dimethoxy-6-methyl-6a-alpha-aporphiniu
g)quinolinium,5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-4h-dibenzo(d
(6aS)-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium
[6aS,(+)]-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium
(6aS)-1,11-Dihydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6aα,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium
5,6,6A(S),7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,G]quinolinium chloride | [Molecular Formula]
C20H24INO4 | [MDL Number]
MFCD00075891 | [MOL File]
2141-09-5.mol | [Molecular Weight]
469.31 |
| Chemical Properties | Back Directory | [Melting point ]
252℃ | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder |
| Hazard Information | Back Directory | [Description]
A wide variety of species contain this quaternary alkaloid which is widespread
among the families, Aquilegia, Magnolia and Michelia. It has been isolated and
characterized as the iodide, m.p. 248-9°C (dec.); [0:11>5 + 200.1° (MeOH). The
optically inactive base also yields an iodide which crystallizes with 1.5 H20,
m.p. 243°C (dec.). | [Chemical Properties]
Off-white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from magnolia, thrush, phellodendron, coptis root, celandine and magnolia. | [Uses]
Magnoflorine-d3 is the labelled analogue of Magnoflorine, an isoquinoline alkaloid from the Coptis japonica and it enhances the myoblast differentiation through activation of the p38 MAP kinase and Akt pathway. | [Definition]
ChEBI:(S)-magnoflorine is an aporphine alkaloid that is (S)-corytuberine in which the nitrogen has been quaternised by an additional methyl group. It has a role as a plant metabolite. It is an aporphine alkaloid and a quaternary ammonium ion. It is functionally related to a (S)-corytuberine. | [storage]
Store at -20°C | [References]
Nakano., Chem. Pharm. Bull. (Tokyo), 2, 329 (1954)
Tomita, Kikkawa.,J. Pharm. Soc., Japan, 77, 195 (1957)
Gopinath et aI., J. Sci. Ind. Res., 18B, 444 (1959)
Ishii, Harada.,J. Pharm. Soc., Japan, 81,238 (1961)
Yang, Lu, Hsiao., ibid, 82,794,816 (1962)
Yang, Lu, Hsiao., ibid, 83,216 (1963) |
|
|