| Identification | Back Directory | [Name]
N-[4-(2-Oxo-2,3-Dihydro-1h-Benzimidazol-1- Yl)Piperidin-1-Ylcarbonyl]-[3(S)-Methyl]-D- Tryptophyl-L-Lysine Tert-Butyl Ester | [CAS]
214348-67-1 | [Synonyms]
L054
L-054
L 054
L-054,522
N-[4-(2-Oxo-2,3-Dihydro-1h-Benzimidazol-1- Yl)Piperidin-1-Ylcarbonyl]-[3(S)-Methyl]-D- Tryptophyl-L-Lysine Tert-Butyl Ester | [Molecular Formula]
C35H47N7O5 | [MDL Number]
MFCD19105487 | [MOL File]
214348-67-1.mol | [Molecular Weight]
645.79 |
| Hazard Information | Back Directory | [Uses]
L-054522 is an agonist for somatostatin receptor subtype 2 with Kd of 0.01 nM. L-054522 inhibits growth hormone release from rat primary pituitary cell (IC50=0.05 nM) and glucagon and insulin release from isolated mouse pancreatic islet cell (IC50=0.05 nM and 12 nM)[1]. | [References]
[1] Yang L, et al., Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10836-41. DOI:10.1073/pnas.95.18.10836 |
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