| Identification | Back Directory | [Name]
2,4-Cyclohexadien-1-one, 3,5-dihydroxy-4,6,6-tris(3-methyl-2-buten-1-yl)-2-(2-methyl-1-oxopropyl)- | [CAS]
21621-94-3 | [Synonyms]
2,4-Cyclohexadien-1-one, 3,5-dihydroxy-4,6,6-tris(3-methyl-2-buten-1-yl)-2-(2-methyl-1-oxopropyl)- | [Molecular Formula]
C25H36O4 | [MOL File]
21621-94-3.mol | [Molecular Weight]
400.55 |
| Hazard Information | Back Directory | [Uses]
Colupulone is a β-acid resin component found in hops (Humulus lupulus) and exhibits antibacterial and anti-larval activity against Culex mosquitoes. Colupulone can be used in studies related to infectious diseases[1][2][3]. | [Definition]
ChEBI: Colupulone is a beta-bitter acid in which the acyl group is specified as isobutanoyl. It is a conjugate acid of a colupulone(1-). | [References]
[1] Connett B E, et al. Chemistry of hop constituents. Part XXXIV. Methylation of some hop resins[J]. Journal of the Chemical Society C: Organic, 1969 (2): 340-344.
[2] Makri A, et al. Colupulone, colupone and novel deoxycohumulone geranyl analogues as larvicidal agents against Culex pipiens. Pest Manag Sci. 2022 Oct;78(10):4217-4222. DOI:10.1002/ps.7039
[3] Li Y, et al. Identification of colupulone and lupulone as the main contributors to the antibacterial activity of hop extracts using activity-guided fractionation and metabolome analysis. Food Res Int. 2023 Jul;169:112832. DOI:10.1016/j.foodres.2023.112832 |
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