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216434-81-0

216434-81-0 Structure

216434-81-0 Structure
IdentificationBack Directory
[Name]

8-BROMOMETHYL-4,4-DIFLUORO-1,3,5,7-TETRAMETHYL-4-BORA-3A,4A-DIAZA-S-INDACENE
[CAS]

216434-81-0
[Synonyms]

meso-CH2Br-BODIPY
BODIPY(R) 493/503 METHYL BROMIDE
8-BROMOMETHYL-4,4-DIFLUORO-1,3,5,7-TETRAMETHYL-4-BORA-3A,4A-DIAZA-S-INDACENE
8-Bromomethyl-4,4-difluoro-1,3,5,7-tetramethyl- 4-bora-3a,4a
-diaza-s-indacene
[Molecular Formula]

C14H16BBrF2N2
[MDL Number]

MFCD00467595
[MOL File]

216434-81-0.mol
[Molecular Weight]

341
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Brown to reddish brown
Safety DataBack Directory
[Symbol(GHS) ]


GHS05,GHS07
[Signal word ]

Danger
[Hazard statements ]

H335-H314
[Precautionary statements ]

P260-P264-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P403+P233-P405-P501
Hazard InformationBack Directory
[Uses]

BODIPY493/503 methyl bromide is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells[1]. Maximum excitation/emission wavelength: 493/503 nm[1].
[References]

[1] Zaiguo Li, et al. Synthesis and spectral properties of cholesterol- and FTY720-containing boron dipyrromethene dyes. Synthesis and spectral properties of cholesterol- and FTY720-containing boron dipyrromethene dyes. J Org Chem. 2007 Oct 26;72(22):8376-82. DOI:10.1021/jo701475q
[2] Bo Qiu, et al. BODIPY 493/503 Staining of Neutral Lipid Droplets for Microscopy and Quantification by Flow Cytometry. Bio Protoc. 2016 Sep 5;6(17):e1912. DOI:10.21769/BioProtoc.1912
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