| Identification | Back Directory | [Name]
4-(7-methoxyquinolin-4-yl)-2-methylphenol | [CAS]
2165340-32-7 | [Synonyms]
CU-CPT-9b
cas 2165340-32-7
CU-CPT-9B, CPD2004
CU-CPT9a >=98% (HPLC)
4-(7-methoxyquinolin-4-yl)-2-methylphenol
2-Methyl-4-(7-methoxy-4-quinolinyl)phenol
CU-CPT-9B;CAS 2165340-32-7 ;TLR8 INHIBITOR
Phenol, 4-(7-methoxy-4-quinolinyl)-2-methyl- | [Molecular Formula]
C17H15NO2 | [MDL Number]
MFCD31689252 | [MOL File]
2165340-32-7.mol | [Molecular Weight]
265.31 |
| Chemical Properties | Back Directory | [Boiling point ]
429.7±45.0 °C(Predicted) | [density ]
1.201±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml | [form ]
A crystalline solid | [pka]
8.47±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
CU-CPT9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells. | [storage]
Store at -20°C |
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