| Identification | Back Directory | [Name]
5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE* | [CAS]
216699-35-3 | [Synonyms]
5-ROX, CXR
5-ROX, >97%
5-ROX, 5-CXR
SYNONYM: 5-ROX
5-ROX [5-Carboxy-X-rhodaMine]
5-Carboxy-X-rhodamine triethylamin salt
5-carboxy-X-rhodaMine, triethylaMMoniuM salt
5-ROX [5-Carboxy-X-rhodamine] *CAS 216699-35-3*
5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*
9-(2,4-Dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium inner salt
1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium,9-(2,4-dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-, inner salt | [Molecular Formula]
C25H23N2O5.2C6H15N.Cl | [MDL Number]
MFCD03453222 | [MOL File]
216699-35-3.mol | [Molecular Weight]
669.302 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
powder to crystal | [color ]
Gray to Dark purple to Black | [InChIKey]
UNGMOMJDNDFGJG-UHFFFAOYSA-N | [SMILES]
C(C1C=C(C(=O)O)C=CC=1C1=C2C=C3CCCN4CCCC(=C34)C2=[O+]C2=C3CCCN4CCCC(=C34)C=C12)(=O)[O-] |
| Hazard Information | Back Directory | [Description]
The carboxylic acid of 5-ROX is used for oligonucleotide labeling and automated DNA sequencing applications. Often a dye of choice for fluorescence resonance energy transfer (FRET) and fluorescence quenching applications. Conjugates of this dye have longer-wavelength spectra than the spectra of Lisaamine™ rhodamine B conjugates, but somewhat shorter-wavelength spectra than those of Texas Red™ conjugates. | [Uses]
5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties | [Definition]
ChEBI: An X-rhodamine triethylammonium salt having a carboxy substituent at the 5-position. | [Chemical Reactivity]
Primary amines | [Abs/Em Maxima]
570/591 nm | [Extinction Coefficient]
93,000 cm-1M-1 | [Spectrally Similar Dyes]
Alexa Fluor® 568, TAMRA, CF™ 568 |
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