ChemicalBook--->CAS DataBase List--->216699-35-3

216699-35-3

216699-35-3 Structure

216699-35-3 Structure
IdentificationBack Directory
[Name]

5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*
[CAS]

216699-35-3
[Synonyms]

5-ROX, CXR
5-ROX, >97%
5-ROX, 5-CXR
SYNONYM: 5-ROX
5-ROX [5-Carboxy-X-rhodaMine]
5-Carboxy-X-rhodamine triethylamin salt
5-carboxy-X-rhodaMine, triethylaMMoniuM salt
5-ROX [5-Carboxy-X-rhodamine] *CAS 216699-35-3*
5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*
9-(2,4-Dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium inner salt
1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium,9-(2,4-dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-, inner salt
[Molecular Formula]

C25H23N2O5.2C6H15N.Cl
[MDL Number]

MFCD03453222
[MOL File]

216699-35-3.mol
[Molecular Weight]

669.302
Chemical PropertiesBack Directory
[storage temp. ]

Inert atmosphere,Store in freezer, under -20°C
[solubility ]

DMSO (Slightly), Methanol (Slightly), Water (Slightly)
[form ]

powder to crystal
[color ]

Gray to Dark purple to Black
[InChIKey]

UNGMOMJDNDFGJG-UHFFFAOYSA-N
[SMILES]

C(C1C=C(C(=O)O)C=CC=1C1=C2C=C3CCCN4CCCC(=C34)C2=[O+]C2=C3CCCN4CCCC(=C34)C=C12)(=O)[O-]
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Flame (GHS02)
GHS07,GHS02
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H226
[Precautionary statements ]

P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[HS Code ]

2934.99.4400
Hazard InformationBack Directory
[Description]

The carboxylic acid of 5-ROX is used for oligonucleotide labeling and automated DNA sequencing applications. Often a dye of choice for fluorescence resonance energy transfer (FRET) and fluorescence quenching applications. Conjugates of this dye have longer-wavelength spectra than the spectra of Lisaamine™ rhodamine B conjugates, but somewhat shorter-wavelength spectra than those of Texas Red™ conjugates.
[Uses]

5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties
[Definition]

ChEBI: An X-rhodamine triethylammonium salt having a carboxy substituent at the 5-position.
[Chemical Reactivity]

Primary amines
[Abs/Em Maxima]

570/591 nm
[Extinction Coefficient]

93,000 cm-1M-1
[Spectrally Similar Dyes]

Alexa Fluor® 568, TAMRA, CF™ 568
Spectrum DetailBack Directory
[Spectrum Detail]

5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*(216699-35-3)1HNMR
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