| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2170695-19-7 | [Synonyms]
VH032-C5-NH2
(S,R,S)-AHPC-C5-NH2
(2S,4R)-1-[(2S)-2-(6-aminohexanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide | [Molecular Formula]
C28H41N5O4S | [MOL File]
2170695-19-7.mol | [Molecular Weight]
543.73 |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-C5-NH2 (VH032-C5-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader[1]. | [IC 50]
VHL | [References]
[1] Lijie Peng, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772. DOI:10.1021/acsmedchemlett.9b00025 |
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