| Identification | Back Directory | [Name]
Sulfo-Cy5.5 maleimide | [CAS]
2183440-58-4 | [Synonyms]
Sulfo-Cy5.5 Mal
Sulfo-Cy5.5 maleimide
Sulfo-Cy5.5 maleimide,Sulfo-Cy5.5 Mal | [Molecular Formula]
C46H49KN4O15S4 | [MOL File]
2183440-58-4.mol | [Molecular Weight]
1065.25 |
| Chemical Properties | Back Directory | [solubility ]
Soluble in water, DMSO, DMF | [Appearance]
Dark blue solid | [ex/em]
678/706 nm (PBS buffer) | [ε(extinction coefficient)]
211000 L⋅mol−1⋅cm−1 | [Φ(quantum yield)]
0.21 | [InChIKey]
XASSSMDYGRGWCK-UHFFFAOYSA-N | [SMILES]
CC1(C(N(CCCCCC(=O)NCCN2C(C=CC2=O)=O)C2C=CC3=C(C=C(S(O)(=O)=O)C=C3C1=2)S(O)(=O)=O)=CC=CC=CC1=[N+](C2C=CC3=C(C=C(S(O)(=O)=O)C=C3C=2C1(C)C)S([O-])(=O)=O)C)C.[KH] |
| Hazard Information | Back Directory | [Description]
Sulfo-Cy5.5 maleimide is a water-soluble dye containing a maleimide group. The sulfo-Cy5.5 has excitation and emission wavelengths around 673/707 nm. The maleimide group commonly reacts with thiol groups to form a thioester bond at pH 6.5 to 7.5. | [Chemical Properties]
Appearance: Dark blue solid
ex/em: 678/706 nm (PBS buffer)
Extinction coefficient (ε): 211000 L??mol??1??cm??1
Quantum yield (Φ): 0.21 | [Uses]
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers[1][2]. | [References]
[1] Duss O, et al. Transient Protein-RNA Interactions Guide Nascent Ribosomal RNA Folding. Cell. 2019 Nov 27;179(6):1357-1369.e16. DOI:10.1016/j.cell.2019.10.035
[2] Ezeani M, et al. Collagen-Targeted Peptides for Molecular Imaging of Diffuse Cardiac Fibrosis. J Am Heart Assoc. 2021 Sep 21;10(18):e022139. DOI:10.1161/JAHA.121.022139 | [Abs/Em Maxima]
673/691 nm | [Fluoresene quantum yield]
0.21 | [Extinction Coefficient]
211000 | [CF260]
0.09 | [CF280]
0.11 |
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