| Identification | Back Directory | [Name]
horminone | [CAS]
21887-01-4 | [Synonyms]
Hormine
Horminon
Nsc122418
Nsc294577
horminone
Aids031165
Aids-031165
7α-Hydroxyroyleanone
7α,12-Dihydroxyabieta-8,12-diene-11,14-dione
7ALPHA,12-DIHYDROXY-8,12-ABIETADIENE-11,14-DIONE
1,4-Phenanthrenedione, 4B,5,6,7,8,8A,9,10-octahydro-3,10-dihydroxy-4B,8,8-trimethyl-2-(1-methylethyl)-
(4bS)-4b,5,6,7,8,8aβ,9,10-Octahydro-3,10β-dihydroxy-2-isopropyl-4bα,8,8-trimethyl-1,4-phenanthrenedione
(4bS)-1,4,4b,5,6,7,8,8aβ,9,10-Decahydro-3,10β-dihydroxy-2-isopropyl-4bα,8,8-trimethyl-1,4-phenanthrenedione
(4bS,8aS,10R)-3,10-dihydroxy-2-isopropyl-4b,8,8-trimethyl-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-1,4-dione
1,4-Phenanthrenedione, 4b,5,6,7,8,8a,9,10-octahydro-3,10-dihydroxy-4b,8,8-trimethyl-2-(1-methylethyl)-, (4bS,8aS,10R)- | [Molecular Formula]
C20H28O4 | [MOL File]
21887-01-4.mol | [Molecular Weight]
332.43 |
| Chemical Properties | Back Directory | [Melting point ]
178 °C | [Boiling point ]
469.3±45.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
4.50±1.00(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
Horminone is an abietan diterpene quinone that can be isolated from Labiatae family. Horminone increases of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels in vivo. Horminone inhibits the growth of Trypanosoma cruzi and shows antibacterial activity[1]. | [Definition]
ChEBI: An abietane diterpenoid that is abieta-8,12-diene substituted by hydroxy groups at positions 7 and 12 and oxo groups at positions 11 and 14 (the 7alpha stereoisomer) . | [target]
DNA/RNA Synthesis | NADPH-oxidase | Antifection | [References]
[1] Inés Nicolás, et al. Theoretical study of the structure and antimicrobial activity of horminone. Theoretical Biochemistry and Biophysics. 2003. |
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