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22006-64-0

22006-64-0 Structure

22006-64-0 Structure
IdentificationBack Directory
[Name]

ACTH (1-13)
[CAS]

22006-64-0
[Synonyms]

acth(1-3)
ACTH (1-13)
SYSMEHFRWGKPV
ACTH (1-13), HUMAN
ACTH?(1-13)/ACTH (1-13), human
ADRENOCORTICOTROPIC HORMONE (1-13)
ADRENOCORTICOTROPIC HORMONE (1-13), HUMAN
adrenocorticotropic hormone fragment*1-13
adrenocorticotropic hormone fragment 1-13, human
SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL
H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-OH
L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-a-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valine
[Molecular Formula]

C75H106N20O19S
[MDL Number]

MFCD00133030
[MOL File]

22006-64-0.mol
[Molecular Weight]

1623.83
Chemical PropertiesBack Directory
[density ]

1.49±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[form ]

Powder
[pka]

3.70±0.10(Predicted)
[color ]

White to off-white
[Sequence]

H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH
Hazard InformationBack Directory
[Uses]

ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.
[in vivo]

ACTH (1-13) alone or in combination with met-enkephalin shows potent cytoprotective effects in the model of ethanol induced gastric lesions in rats, and has immunomodulatory effects[1].

[References]

[1] Mulabegovi? N, et al. Pharmacodynamic properties of a combination of met-enkephalin and alpha 1-13 adrenocorticotropic hormone. Med Arh. 2008;62(1):41-4. PMID:18543754
[2] Allen MJ, et al. Adrenocorticotropic Hormone (ACTH). StatPearls. 2018.7. PMID:29763207
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