| Identification | Back Directory | [Name]
Z-Val-Ala-DL-Asp-fluoromethylketone | [CAS]
220644-02-0 | [Synonyms]
Z-Val-Ala-DL-Asp-fluoromethylketone (N-1510.0005)
L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]- | [Molecular Formula]
C21H28FN3O7 | [MDL Number]
MFCD06795862 | [MOL File]
220644-02-0.mol | [Molecular Weight]
453.46 |
| Hazard Information | Back Directory | [Uses]
Z-VA-DL-D-FMK (Z-VA-DL-D(OH)-FMK) is an inhibitor for caspase[1]. Z-VA-DL-D-FMK binds irreversibly to caspases, increases the sensitivity of TNF-α, and activates HIV replication in infected T cell ACH-2[1]. | [References]
[1] Scheller C, et al., Caspase inhibition activates HIV in latently infected cells. Role of tumor necrosis factor receptor 1 and CD95. J Biol Chem. 2002 May 3;277(18):15459-64. DOI:10.1074/jbc.M200763200 |
|
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
| Company Name: |
Abcam Limited
|
| Tel: |
021-2070050 400921018 |
| Website: |
www.abcam.cn |
|